Drosophila Polymorphism Database (DPDB)A Portal for Nucleotide Polymorphism in Drosophila
نویسندگان
چکیده
منابع مشابه
Nucleotide polymorphism at the xanthine dehydrogenase locus in Drosophila pseudoobscura.
Sequential polyacrylamide electrophoresis has revealed 20 allozymes of xanthine dehydrogenase (XDH) in Drosophila pseudoobscura. DNA sequence determination of seven isolates of the Xdh locus that represent six allozyme classes are presented here. Of the 5,456 sites examined, 180 are polymorphic, with 27 polymorphisms occurring at nonsynonymous, or replacement, sites. An average of nine amino ac...
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Population genetic theory predicts that selectively driven changes of allele frequency for both beneficial and deleterious mutants reduce polymorphism at tightly linked sites. All else being equal, these reductions in polymorphism are expected to be greater when recombination rates are lower. Therefore, the empirical observation of a positive correlation between recombination rates and amounts ...
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Several biochemical studies have suggested that in Drosophila melanoguster the two common allozymes of G6PD differ in their in vitro activities and thermal stabilities. Yei, it remains to be shown that these characterizations reflect actual in vivo differences and are not artifacts of the biochemical approach. In this study it is shown that in vivo activity differences must exist between these ...
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HE population geneticist is essentially interested in the variation of gene freTquencies in natural populations. Within chromosomal inversions blocks of genes are contained and in many species of Drosophila due to the presence of easily analysable giant chromosomes, the behavior of these blocks of genes can be easily studied in natural populations. Thus, of recent years chromosomal inversion po...
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TUDY of the naturally occurring polymorphism found in the banded polytene Schromosomes of Diptera has yielded a great deal of information on the genetic structure of natu -a1 populations, and also in some instances has indicated the pattern of evolut .onary change which has occurred during species formation. Outstanding examples of studies of the latter sort are those in the Drosophila obscura ...
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ژورنال
عنوان ژورنال: Fly
سال: 2007
ISSN: 1933-6934,1933-6942
DOI: 10.4161/fly.5043